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Can I Switch from Ozempic to Wegovy for Weight Loss? A Comprehensive Guide


As it has been recently made available in the UK, many people who have previously been on Ozempic are considering the switch. With new medicines being developed all the time, it’s normal to wonder how they compare and if it’s safe to switch between them. 

Recently, there’s been a lot of talk about comparing Wegovy to Ozempic. If you’re trying to lose weight, you might be wondering if switching from one to the other is a good idea. Read our comprehensive guide to the differences.

Although they have different trade names, both Ozempic and Wegovy contain the same active ingredient, semaglutide. They belong to the class of GLP-1 receptor agonists, recognised for their effectiveness in facilitating weight loss while also managing blood sugar levels in individuals with type 2 diabetes. Both medications function by replicating the actions of GLP-1, a hormone integral to appetite regulation and the promotion of feelings of fullness.

So, what is the difference between Ozempic and Wegovy? 

Firstly, Wegovy is licensed for weight management and obesity in the UK, while Ozempic is only licensed for diabetes management. This is reflected in the UK’s National Institute for Health and Care (NICE) guidelines. 

Additionally, Wegovy is also available in higher doses. While you can only get up to 1mg of Ozempic, there are an additional 1.7mg and 2mg of Wegovy available. 

Recent research conducted by Dr. Gurdeep Singh and collaborators offers valuable insights into the outcomes of pivotal clinical trials, including SUSTAIN (Semaglutide Unabated Sustainability in Treatment of Type 2 Diabetes), PIONEER (Peptide Innovation for Early Diabetes Treatment), and STEP (Semaglutide Treatment Effect in People with Obesity). These trials examined the impact of semaglutide, administered orally or via injection, on weight loss among individuals with type 2 diabetes or obesity. The findings from these trials, along with additional scholarly contributions, have played a significant role in securing NICE approval for Wegovy (semaglutide) as a treatment option for weight loss.

While Ozempic has been widely used for glycaemic control and weight reduction in individuals with type 2 diabetes, Wegovy is specifically approved for weight management in individuals with obesity or overweight conditions. However, it is important to consider dosage adjustments under medical supervision while transitioning from Ozempic to Wegovy to ensure optimal efficacy and safety. 

Read more: Buy Wegovy in the UK 

Buy Wegovy in the UK

Both Ozempic and Wegovy are generally well-tolerated, with common side effects including nausea, vomiting, diarrhoea, and abdominal discomfort. However, it is a good idea to consult with your healthcare provider, who can offer guidance on managing side effects and addressing any concerns that may arise during the transition process.

If you are considering switching from Ozempic to Wegovy, reach out to a healthcare professional or contact the Semapen team, as we can offer you the best advice by taking into account individual health status, treatment goals, and preferences.

While weight loss medication plays a crucial role in weight management, lifestyle modifications such as diet and exercise remain cornerstone components of a comprehensive treatment approach. The clinical trials of the NHS emphasise the importance of adopting healthy habits to complement medication therapy and maximise weight loss outcomes. Patients are encouraged to work closely with healthcare providers or weight loss programme providers to develop personalised diet and exercise plans that align with their treatment goals. Semapen offers personalised clinical support when you sign up for our Semapen programme.

In conclusion, while Ozempic and Wegovy offer promising prospects for weight loss and metabolic control, Wegovy is licensed to treat obesity in the UK, whilst Ozempic is only licensed for diabetes treatment.  With the right support and guidance from Semapen, switching to Wegovy can be a positive step towards improved health and well-being.  



Singh G, Krauthamer M, Bjalme-Evans M. Wegovy (Semaglutide): A New Weight Loss Drug for Chronic Weight Management. Journal of Investigative Medicine. 2022;70(1):5-13. doi:10.1136/jim-2021-001952