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Mounjaro

Learn more about Mounjaro
The revolutionary new treatment for weight loss

About Mounjaro

Mounjaro (also known as tirzepatide) is the latest in a class of weight loss injections that are proven to dramatically reduce weight and the severity of type 2 diabetes.

Like Wegovy (semaglutide), Mounjaro mimics the effects of natural hormones called incretins that control hunger, appetite, and blood sugar levels. 

The key difference in the way Wegovy and Mounjaro work is that Wegovy mimics the effect of one of the three main incretin hormones in the body (GLP1), whereas Mounjaro is a ‘Twincretin’ that mimics the effect of two (both GLP1 and another called GIP). 

This ‘Twincretin’ double effect of Mounjaro was shown to produce an average of 21% weight loss, compared to about 15% with Wegovy.

How Mounjaro Works

The Science of Weight Loss

Mounjaro has three distinct actions:

Suppresses Appetite:

Mounjaro stimulates GLP-1 and GIP receptors, which reduces the desire to eat and creates a feeling of early fullness. This makes it easier to control your appetite, portion size, and hunger pangs.

Boosts Metabolism:

Mounjaro stimulates insulin release, which controls blood sugar and enhances the body’s metabolism, promoting energy expenditure and contributing to weight loss.

Reduces dangerous visceral (‘belly’) fat:

As you lose weight on Mounjaro, for everyone part of lean (muscle) mass lost, patients lose 3 times as much fat mass, particularly the more dangerous visceral ‘belly’ fat that is associated with heart disease and diabetes. Explore our Mounjaro-related blogs to get all your questions answered.

Suppresses Appetite

Boosts Metabolism

Reduces visceral fat

Lose Weight with Mounjaro

You can expect to lose an average of 21% of your body weight (mostly within 3 months) and maintain this for up to 72 weeks if you continue on treatment.

*https://www.nejm.org/doi/full/10.1056/NEJMoa2206038

Mounjaro vs Wegovy:

 

Mounjaro

 

 

Wegovy

Active ingredient Tirzepatide Semaglutide
Mechanism of Action Stimulates GLP-1 and GIP action Stimulates GLP-1 action
Dosage Once weekly injection Once weekly injection
Number of months to reach the maximum dose 6 5
Average Weight Loss (non-diabetic) 21% 15%
Side Effects Similar to Wegovy but with less nausea.

Hair thinning (temporary) reported – daily multivitamins are advised.

Interferes with the action of the oral contraceptive pill.

 

 

Nausea, constipation, diarrhea, vomiting, acid reflux, belching, and bloating are the most common.

 

 

Availability in the UK Available Available

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