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What Foods Should I Avoid to Maximise Weight Loss with Mounjaro?


When optimising weight loss with Mounjaro, there are several key dietary considerations to keep in mind, guided by UK dietary guidelines. Let’s dive into the types of foods it might be wise to limit or avoid to maximise the effects of this medication.

Avoiding Fatty Foods

When using Mounjaro to support your weight loss goals, it’s crucial to be mindful of the types of fats you consume. Saturated fats, found in many foods such as confectionery, biscuits, and fatty cuts of meat, should be consumed in moderation because they raise the level of LDL ‘bad’ cholesterol in the blood.

Additionally, trans fats, often found in fried foods and baked goods, pose significant health risks and can impact your weight loss efforts. Similarly, palm oil and coconut oil, rich in saturated fats, should be substituted with healthier alternatives like olive oil or canola oil, as they contain mostly unsaturated fats. Adhering to the UK’s Eatwell Guide by choosing healthier unsaturated fats can improve blood cholesterol levels and reduce heart disease risks, thus enhancing the effectiveness of Mounjaro in your weight management journey.

Sugar and Refined Carbohydrates

Be mindful of refined carbohydrates and sugary foods, as they are often high in calories and low in nutritional value, which may slow down weight loss. Items such as white bread, pastries, sweets, sodas, and certain fruit juices cause rapid spikes in blood sugar levels, which may hinder weight management. Reducing the intake of free sugars supports weight loss on Mounjaro.

High-Sodium Foods

Salt, while common in many diets, should be used sparingly. High sodium intake is linked with increased blood pressure, which poses a risk for heart disease and stroke. The NHS recommends consuming no more than 6 grams of salt daily for adults. It’s important to be mindful of salt levels, especially in sauces, dressings, and pre-packaged foods, which can be significant sources of sodium. By managing salt intake alongside Mounjaro usage, individuals can optimise their weight loss journey while also promoting heart health.

Alcohol: Drink in Moderation

Research indicates that alcohol consumption, particularly heavy drinking, can contribute to weight gain and obesity. However, it’s important to consider that individual responses to alcohol can vary, and factors such as the type of alcoholic beverage consumed, overall diet, lifestyle factors, and genetics may all play a role in how alcohol affects weight management. Ultimately, when it comes to alcohol and weight management, moderation is key. While moderate alcohol consumption may not necessarily hinder weight loss efforts, excessive drinking can contribute to weight gain and other health problems. As always, it’s best to consult with a healthcare professional for personalised advice and guidance tailored to individual health needs and goals.

Tailoring Your Diet to Your Needs

Since there’s no one-size-fits-all diet for everyone taking Mounjaro, working with your healthcare provider to create a personalised diet plan is essential. If you are in a SemaPen weight loss programme, you will receive 1:1 clinical support and nutrition support with a dedicated nutritionist to support your weight loss programme. Ultimately, a balanced diet rich in fresh fruits, vegetables, whole grains, lean proteins, and low-fat dairy, while avoiding high-fat, high-sugar, and high-sodium foods, can greatly enhance the effectiveness of your weight loss and support your use of Mounjaro in your weight management journey. This approach promotes overall health and well-being, ensuring that you’re not just losing weight but also nourishing your body adequately.

Incorporating these dietary adjustments while taking Mounjaro can help you achieve better results. Always work closely with your healthcare provider or your weight loss provider to adapt these recommendations to your personal needs, as individual responses to diet and medication can vary.

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NHS Eatwell Guide

MHRA authorises diabetes drug Mounjaro (Tirzepatide) for weight management and weight loss

Xu, Y. et al. (2023). “Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes.” American Journal of Cardiology, 213, 1599-1606.

Chiu, S., Williams, P.T., and Krauss, R.M. (2017). “Clinical Outcomes of Dietary Replacement of Saturated Fat with Polyunsaturated Fat in the Meta-Analysis of Randomised Controlled Trials.” Annals of Nutrition and Metabolism, 71(1-2), pp.107-117.